NARWHAL, a primary analysis pipeline for NGS data | Zendy

Rutger W. W. Brouwer | Zendy; Mirjam C. G. N. van den Hout | Zendy; Frank Grosveld | Zendy; Wilfred F. J. van IJcken | Zendy

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NARWHAL, a primary analysis pipeline for NGS data

Author(s) -

Rutger W. W. Brouwer,

Mirjam C. G. N. van den Hout,

Frank Grosveld,

Wilfred F. J. van IJcken

Publication year - 2011

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr613

Subject(s) - pipeline (software) , computer science , software , sample (material) , data mining , trac , sequence assembly , computational biology , programming language , biology , genetics , chemistry , gene expression , transcriptome , chromatography , gene

The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open-source aligners and automated quality assessment. The entire pipeline can be run using only one simple sample-sheet for diverse sequencing applications. NARWHAL creates a sample-oriented data structure and outperforms existing tools in speed.

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