Feature-based 3D motif filtering for ribosomal RNA | Zendy

Ying Shen | Zendy; Hau−San Wong | Zendy; Shaohong Zhang | Zendy; Zhiwen Yu | Zendy

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Feature-based 3D motif filtering for ribosomal RNA

Author(s) -

Ying Shen,

Hau−San Wong,

Shaohong Zhang,

Zhiwen Yu

Publication year - 2011

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr495

Subject(s) - rna , computational biology , structural motif , motif (music) , computer science , nucleic acid structure , pattern recognition (psychology) , artificial intelligence , algorithm , biology , gene , genetics , physics , biochemistry , acoustics

RNA 3D motifs are recurrent substructures in an RNA subunit and are building blocks of the RNA architecture. They play an important role in binding proteins and consolidating RNA tertiary structures. RNA 3D motif searching consists of two steps: candidate generation and candidate filtering. We proposed a novel method, known as Feature-based RNA Motif Filtering (FRMF), for identifying motifs based on a set of moment invariants and the Earth Mover's Distance in the second step.

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