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Production and degradation of RNA and proteins are stochastic processes, difficulting the distinction between spurious fluctuations in their numbers and changes in the dynamics of a genetic circuit. An accurate method of change detection is key to analyze plasticity and robustness of stochastic genetic circuits.

bioinformatics

Automatic detection of changes in the dynamics of delayed stochastic gene networks and <i>in vivo</i> production of RNA molecules in <i>Escherichia coli</i>

Automatic detection of changes in the dynamics of delayed stochastic gene networks and in vivo production of RNA molecules in Escherichia coli