Automatic detection of changes in the dynamics of delayed stochastic gene networks and in vivo production of RNA molecules in Escherichia coli | Zendy

Jarno Mäkelä | Zendy; Heikki Huttunen | Zendy; Meenakshisundaram Kandhavelu | Zendy; Olli YliHarja | Zendy; André S. Ribeiro | Zendy

Open Access

Automatic detection of changes in the dynamics of delayed stochastic gene networks and in vivo production of RNA molecules in Escherichia coli

Author(s) -

Jarno Mäkelä,

Heikki Huttunen,

Meenakshisundaram Kandhavelu,

Olli YliHarja,

André S. Ribeiro

Publication year - 2011

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr471

Subject(s) - escherichia coli , in vivo , dynamics (music) , rna , gene , computational biology , biology , production (economics) , genetics , physics , macroeconomics , acoustics , economics

Production and degradation of RNA and proteins are stochastic processes, difficulting the distinction between spurious fluctuations in their numbers and changes in the dynamics of a genetic circuit. An accurate method of change detection is key to analyze plasticity and robustness of stochastic genetic circuits.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research