Open AccessDiscovering novel subsystems using comparative genomics
Author(s) -
Luciana Ferrer,
Alexander G. Shearer,
Peter D. Karp
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr428
Subject(s) - genome , annotation , context (archaeology) , computational biology , comparative genomics , genomics , gene , gene annotation , structural genomics , function (biology) , gene prediction , biology , functional genomics , computer science , genetics , protein structure , paleontology , biochemistry
Key problems for computational genomics include discovering novel pathways in genome data, and discovering functional interaction partners for genes to define new members of partially elucidated pathways.
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