Identification of novel phosphorylation modification sites in human proteins that originated after the human–chimpanzee divergence
Author(s) -
Dong Seon Kim,
Yoonsoo Hahn
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr426
Subject(s) - identification (biology) , phosphorylation , divergence (linguistics) , computational biology , human proteins , biology , evolutionary biology , genetics , gene , ecology , linguistics , philosophy
Phosphorylation modifications of specific protein residues are involved in a wide range of biological processes such as modulation of intracellular signal networks. Here, we present the development and application of a bioinformatics procedure for systematic identification of human-specific phosphorylation sites in proteins that may have occurred after the human-chimpanzee divergence.
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