ODORactor: a web server for deciphering olfactory coding
Author(s) -
Xinyi Liu,
Xubo Su,
Fei Wang,
Zhimin Huang,
Qi Wang,
Zhen Li,
Ruina Zhang,
Lifang Wu,
Yi Pan,
Yingyi Chen,
Hanyi Zhuang,
Guoqiang Chen,
Ting Shi,
Jian Zhang
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr385
Subject(s) - computer science , decipher , olfaction , web server , olfactory system , coding (social sciences) , source code , world wide web , the internet , computational biology , bioinformatics , biology , neuroscience , programming language , statistics , mathematics
ODORactor is an open access web server aimed at providing a platform for identifying odorant receptors (ORs) for small molecules and for browsing existing OR-ligand pairs. It enables the prediction of ORs from the molecular structures of arbitrary chemicals by integrating two individual functionalities: odorant verification and OR recognition. The prediction of the ORs for several odorants was experimentally validated in the study. In addition, ODORactor features a comprehensive repertoire of olfactory information that has been manually curated from literature. Therefore, ODORactor may provide an effective way to decipher olfactory coding and could be a useful server tool for both basic olfaction research in academia and for odorant discovery in industry.
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