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Biologically inspired EM image alignment and neural reconstruction
Author(s) -
Seymour Knowles-Barley,
Nancy J. Butcher,
Ian A. Meinertzhagen,
J. Douglas Armstrong
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr378
Subject(s) - computer science , artificial intelligence , pattern recognition (psychology) , computer vision , dynamic programming , segmentation , shortest path problem , algorithm , theoretical computer science , graph
Three-dimensional reconstruction of consecutive serial-section transmission electron microscopy (ssTEM) images of neural tissue currently requires many hours of manual tracing and annotation. Several computational techniques have already been applied to ssTEM images to facilitate 3D reconstruction and ease this burden.

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