RNASAlign: RNA Structural Alignment System | Zendy

Thomas K. F. Wong | Zendy; Kwok-Lung Wan | Zendy; Bay-Yuan Hsu | Zendy; Brenda W. Y. Cheung | Zendy; Wing-Kai Hon | Zendy; TakWah Lam | Zendy; SiuMing Yiu | Zendy

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RNASAlign: RNA Structural Alignment System

Author(s) -

Thomas K. F. Wong,

Kwok-Lung Wan,

Bay-Yuan Hsu,

Brenda W. Y. Cheung,

Wing-Kai Hon,

TakWah Lam,

SiuMing Yiu

Publication year - 2011

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr338

Subject(s) - pseudoknot , computer science , rna , software , structural alignment , sequence alignment , structural bioinformatics , coding (social sciences) , nucleic acid structure , multiple sequence alignment , computational biology , data mining , theoretical computer science , biology , protein structure , genetics , mathematics , programming language , biochemistry , statistics , gene , peptide sequence

Structural alignment of RNA is found to be a useful computational technique for idenitfying non-coding RNAs (ncRNAs). However, existing tools do not handle structures with pseudoknots. Although algorithms exist that can handle structural alignment for different types of pseudoknots, no software tools are available and users have to determine the type of pseudoknots to select the appropriate algoirthm to use which limits the usage of structural alignment in identifying novel ncRNAs.

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