Sensitive and fast mapping of di-base encoded reads
Author(s) -
Farhad Hormozdiari,
Faraz Hach,
S. Cenk Ṣahinalp,
Evan E. Eichler,
Can Alkan
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr303
Subject(s) - computer science , sequence (biology) , genome , software , source code , code (set theory) , computational biology , biology , genetics , gene , set (abstract data type) , programming language , operating system
Discovering variation among high-throughput sequenced genomes relies on efficient and effective mapping of sequence reads. The speed, sensitivity and accuracy of read mapping are crucial to determining the full spectrum of single nucleotide variants (SNVs) as well as structural variants (SVs) in the donor genomes analyzed.
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