An integrative clustering and modeling algorithm for dynamical gene expression data
Author(s) -
Julia Sivriver,
Naomi Habib,
Nir Friedman
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr250
Subject(s) - cluster analysis , computer science , representation (politics) , dynamical systems theory , gene expression , expression (computer science) , dynamics (music) , algorithm , code (set theory) , gene , computational biology , artificial intelligence , biology , physics , genetics , set (abstract data type) , quantum mechanics , politics , political science , acoustics , law , programming language
The precise dynamics of gene expression is often crucial for proper response to stimuli. Time-course gene-expression profiles can provide insights about the dynamics of many cellular responses, but are often noisy and measured at arbitrary intervals, posing a major analysis challenge.
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