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Reasoning with bio-ontologies: using relational closure rules to enable practical querying
Author(s) -
Ward Blondé,
Vladimir Mironov,
Aravind Venkatesan,
Erick Antezana,
Bernard De Baets,
Martin Kuiper
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr164
Subject(s) - computer science , ontology , open biomedical ontologies , idef5 , relation (database) , knowledge base , knowledge representation and reasoning , rdf , vocabulary , description logic , semantics (computer science) , web ontology language , ontology language , semantic web , process (computing) , controlled vocabulary , information retrieval , ontology components , process ontology , world wide web , artificial intelligence , database , programming language , suggested upper merged ontology , philosophy , linguistics , epistemology
Ontologies have become indispensable in the Life Sciences for managing large amounts of knowledge. The use of logics in ontologies ranges from sound modelling to practical querying of that knowledge, thus adding a considerable value. We conceive reasoning on bio-ontologies as a semi-automated process in three steps: (i) defining a logic-based representation language; (ii) building a consistent ontology using that language; and (iii) exploiting the ontology through querying.

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