CMView: Interactive contact map visualization and analysis
Author(s) -
Corinna Vehlow,
Henning Stehr,
Matthias Winkelmann,
José M. Duarte,
Lars Petzold,
Juliane Dinse,
Michael Lappé
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr163
Subject(s) - visualization , computer science , mit license , interactive visualization , software , domain (mathematical analysis) , source code , software visualization , computer graphics (images) , data mining , programming language , software development , mathematical analysis , software construction , mathematics
Contact maps are a valuable visualization tool in structural biology. They are a convenient way to display proteins in two dimensions and to quickly identify structural features such as domain architecture, secondary structure and contact clusters. We developed a tool called CMView which integrates rich contact map analysis with 3D visualization using PyMol. Our tool provides functions for contact map calculation from structure, basic editing, visualization in contact map and 3D space and structural comparison with different built-in alignment methods. A unique feature is the interactive refinement of structural alignments based on user selected substructures.
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