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A wholly defined Agilent microarray spike-in dataset
Author(s) -
Qianqian Zhu,
Jeffrey C. Miecznikowski,
Marc S. Halfon
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr135
Subject(s) - spike (software development) , computer science , dna microarray , r package , pattern recognition (psychology) , microarray analysis techniques , data mining , artificial intelligence , biology , gene , gene expression , genetics , software engineering , computational science
Spike-in datasets provide a valuable resource for assessing and comparing among competing microarray analysis strategies. Our previous wholly defined spike-in datasets, the Golden and Platinum Spikes, have provided insights for the analysis of Affymetrix GeneChips. However, a similar dataset, in which all cRNA identities and relative levels are known prospectively, has not been available for two-color platforms.

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