SHRiMP2: Sensitive yet Practical Short Read Mapping
Author(s) -
Matei David,
Misko Dzamba,
D. A. LISTER,
Lucian Ilie,
Michael Brudno
Publication year - 2011
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btr046
Subject(s) - executable , computer science , shrimp , space (punctuation) , sensitivity (control systems) , source code , code (set theory) , data mining , programming language , biology , operating system , engineering , set (abstract data type) , electronic engineering , fishery
We report on a major update (version 2) of the original SHort Read Mapping Program (SHRiMP). SHRiMP2 primarily targets mapping sensitivity, and is able to achieve high accuracy at a very reasonable speed. SHRiMP2 supports both letter space and color space (AB/SOLiD) reads, enables for direct alignment of paired reads and uses parallel computation to fully utilize multi-core architectures.
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