PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya | Zendy

Xuejian Xiong | Zendy; Hongyan Song | Zendy; Tuan On | Zendy; Lucas Lochovsky | Zendy; Nicholas J. Provart | Zendy; John Parkinson | Zendy

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PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya

Author(s) -

Xuejian Xiong,

Hongyan Song,

Tuan On,

Lucas Lochovsky,

Nicholas J. Provart,

John Parkinson

Publication year - 2011

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr023

Subject(s) - phylogenetic tree , visualization , computer science , web application , world wide web , data science , computational biology , data mining , biology , genetics , gene

With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionary trajectories of user-defined subsets of model organism genes. Applied to pathways or complexes, PhyloPro allows the user to rapidly identify core conserved elements of biological processes together with those that may represent lineage-specific innovations. PhyloPro thus provides a valuable resource for the evolutionary and comparative studies of biological systems.

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