Alignment-free estimation of nucleotide diversity | Zendy

Bernhard Haubold | Zendy; Floyd A. Reed | Zendy; Peter Pfaffelhuber | Zendy

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Alignment-free estimation of nucleotide diversity

Author(s) -

Bernhard Haubold,

Floyd A. Reed,

Peter Pfaffelhuber

Publication year - 2010

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btq689

Subject(s) - estimation , diversity (politics) , nucleotide diversity , computer science , nucleotide , computational biology , genetics , biology , statistics , mathematics , genotype , gene , economics , management , sociology , anthropology , haplotype

Sequencing capacity is currently growing more rapidly than CPU speed, leading to an analysis bottleneck in many genome projects. Alignment-free sequence analysis methods tend to be more efficient than their alignment-based counterparts. They may, therefore, be important in the long run for keeping sequence analysis abreast with sequencing.

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