Open AccessHiTEC: accurate error correction in high-throughput sequencing data
Author(s) -
Lucian Ilie,
Farideh Fazayeli,
Silvana Ilie
Publication year - 2010
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btq653
Subject(s) - computer science , throughput , dna sequencing , source code , algorithm , biology , dna , genetics , telecommunications , wireless , operating system
High-throughput sequencing technologies produce very large amounts of data and sequencing errors constitute one of the major problems in analyzing such data. Current algorithms for correcting these errors are not very accurate and do not automatically adapt to the given data.
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