Generation of a consensus protein domain dictionary | Zendy

R. Dustin Schaeffer | Zendy; Amanda L. Jonsson | Zendy; Andrew M. Simms | Zendy; Valerie Daggett | Zendy

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Generation of a consensus protein domain dictionary

Author(s) -

R. Dustin Schaeffer,

Amanda L. Jonsson,

Andrew M. Simms,

Valerie Daggett

Publication year - 2010

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btq625

Subject(s) - computer science , domain (mathematical analysis) , globular protein , protein folding , protein domain , computational biology , set (abstract data type) , folding (dsp implementation) , protein structure prediction , function (biology) , protein structure , biology , programming language , mathematics , chemistry , crystallography , genetics , engineering , mathematical analysis , biochemistry , electrical engineering , gene

The discovery of new protein folds is a relatively rare occurrence even as the rate of protein structure determination increases. This rarity reinforces the concept of folds as reusable units of structure and function shared by diverse proteins. If the folding mechanism of proteins is largely determined by their topology, then the folding pathways of members of existing folds could encompass the full set used by globular protein domains.

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