A stochastic expectation and maximization algorithm for detecting quantitative trait-associated genes | Zendy

Haimao Zhan | Zendy; Xin Chen | Zendy; Shizhong Xu | Zendy

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A stochastic expectation and maximization algorithm for detecting quantitative trait-associated genes

Author(s) -

Haimao Zhan,

Xin Chen,

Shizhong Xu

Publication year - 2010

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btq558

Subject(s) - maximization , computer science , expectation–maximization algorithm , trait , algorithm , computational biology , maximum likelihood , mathematics , statistics , mathematical optimization , biology , programming language

Most biological traits may be correlated with the underlying gene expression patterns that are partially determined by DNA sequence variation. The correlations between gene expressions and quantitative traits are essential for understanding the functions of genes and dissecting gene regulatory networks.

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