GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base | Zendy

George Khelashvili | Zendy; Kevin C. Dorff | Zendy; Jufang Shan | Zendy; Marta CamachoArtacho | Zendy; Lucy Skrabanek | Zendy; Bas Vroling | Zendy; Michel Bouvier | Zendy; Lakshmi A. Devi | Zendy; Susan R. George | Zendy; Jonathan A. Javitch | Zendy; Martin J. Lohse | Zendy; Graeme Milligan | Zendy; Richard R. Neubig | Zendy; Krzysztof Palczewski | Zendy; Marc Parmentier | Zendy; JeanPhilippe Pin | Zendy; Gerrit Vriend | Zendy; Fabien Campagne | Zendy; Marta Filizola | Zendy

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GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

Author(s) -

George Khelashvili,

Kevin C. Dorff,

Jufang Shan,

Marta CamachoArtacho,

Lucy Skrabanek,

Bas Vroling,

Michel Bouvier,

Lakshmi A. Devi,

Susan R. George,

Jonathan A. Javitch,

Martin J. Lohse,

Graeme Milligan,

Richard R. Neubig,

Krzysztof Palczewski,

Marc Parmentier,

JeanPhilippe Pin,

Gerrit Vriend,

Fabien Campagne,

Marta Filizola

Publication year - 2010

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btq264

Subject(s) - oligomer , g protein coupled receptor , base (topology) , receptor , computer science , computational biology , chemistry , biology , biochemistry , mathematics , polymer chemistry , mathematical analysis

Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.

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