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SICAGO: Semi-supervised cluster analysis using semantic distance between gene pairs in Gene Ontology
Author(s) -
BoYeong Kang,
Song Ko,
DaeWon Kim
Publication year - 2010
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btq133
Subject(s) - gene ontology , cluster analysis , computer science , ontology , cluster (spacecraft) , semantic similarity , data mining , software , artificial intelligence , gene , natural language processing , information retrieval , biology , gene expression , genetics , philosophy , epistemology , programming language
Despite the importance of using the semantic distance to improve the performance of conventional expression-based clustering, there are few freely available software that provides a clustering algorithm using the ontology-based semantic distances as prior knowledge. Here, we present the SICAGO (SemI-supervised Cluster Analysis using semantic distance between gene pairs in Gene Ontology) system that helps to discover the groups of genes more effectively using prior knowledge extracted from Gene Ontology.

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