Open AccessPrediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning
Author(s) -
Chia-Chin Wu,
Shahab Asgharzadeh,
Timothy J. Triche,
David Z. D’Argenio
Publication year - 2010
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btq044
Subject(s) - computer science , ensemble learning , artificial intelligence , machine learning
Three major problems confront the construction of a human genetic network from heterogeneous genomics data using kernel-based approaches: definition of a robust gold-standard negative set, large-scale learning and massive missing data values.
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