Open AccessA censored beta mixture model for the estimation of the proportion of non-differentially expressed genes
Author(s) -
Anastasios Markitsis,
Yinglei Lai
Publication year - 2010
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btq001
Subject(s) - censoring (clinical trials) , computer science , estimation , variance (accounting) , data mining , code (set theory) , statistics , mathematics , engineering , accounting , systems engineering , business , set (abstract data type) , programming language
The proportion of non-differentially expressed genes (pi(0)) is an important quantity in microarray data analysis. Although many statistical methods have been proposed for its estimation, it is still necessary to develop more efficient methods.
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