emPAI Calc—for the estimation of protein abundance from large-scale identification data by liquid chromatography-tandem mass spectrometry | Zendy

Kosaku Shinoda | Zendy; Masaru Tomita | Zendy; Yasushi Ishihama | Zendy

Open Access

emPAI Calc—for the estimation of protein abundance from large-scale identification data by liquid chromatography-tandem mass spectrometry

Author(s) -

Kosaku Shinoda,

Masaru Tomita,

Yasushi Ishihama

Publication year - 2009

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btp700

Subject(s) - mass spectrometry , mascot , abundance (ecology) , tandem mass spectrometry , identification (biology) , chromatography , scale (ratio) , chemistry , computer science , biology , botany , physics , quantum mechanics , fishery , political science , law

emPAI Calc is an open-source web application for the estimation of protein abundance. It uses the correlation between the number of identified peptides and protein abundance in mass spectrometry-based proteomic experiments. The program is the first implementation of our previously reported emPAI algorithm; it calculates the emPAI from the protein identification results obtained by database search engines such as Mascot.

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