The Gene Interaction Miner: a new tool for data mining contextual information for protein–protein interaction analysis
Author(s) -
Aaron Ikin,
Carlos Riveros,
Pablo Moscato,
Alexandre Mendes
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp652
Subject(s) - computer science , data mining , protein–protein interaction , computational biology , biology , genetics
This work was motivated by the need for an automated tool for discovery of genetic networks and the availability of extensive contextual protein-protein interaction information in the iHOP repository. At the moment, this information cannot be explored to its full potential due to the lack of software tools to reliably collect, process and display that information in a way that life scientists can quickly analyze genes of interest and search for potential interaction networks. Commercial tools can perform a similar job, but results appear to be less informative than those obtained using contextual information.
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