mimiRNA: a microRNA expression profiler and classification resource designed to identify functional correlations between microRNAs and their targets | Zendy

William Ritchie | Zendy; Stéphane Flamant | Zendy; John E.J. Rasko | Zendy

Open Access

mimiRNA: a microRNA expression profiler and classification resource designed to identify functional correlations between microRNAs and their targets

Author(s) -

William Ritchie,

Stéphane Flamant,

John E.J. Rasko

Publication year - 2009

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btp649

Subject(s) - microrna , expression (computer science) , computational biology , computer science , resource (disambiguation) , biology , genetics , gene , computer network , programming language

microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by inhibiting target mRNA genes. Their tissue- and disease-specific expression patterns have immense therapeutic and diagnostic potential. To understand these patterns, a reliable compilation of miRNA and mRNA expression data is required to compare multiple tissue types. Moreover, with the appropriate statistical tools, such a resource could be interrogated to discover functionally related miRNA-mRNA pairs.

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