Identification of non-Hodgkin's lymphoma prognosis signatures using the CTGDR method
Author(s) -
Shuangge Ma,
Yawei Zhang,
Jian Huang,
Xuesong Han,
Theodore R. Holford,
Qing Lan,
Nathaniel Rothman,
Peter Boyle,
Tongzhang Zheng
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp604
Subject(s) - single nucleotide polymorphism , snp , biology , computational biology , gene , genetics , genotype
Although NHL (non-Hodgkin's lymphoma) is the fifth leading cause of cancer incidence and mortality in the USA, it remains poorly understood and is largely incurable. Biomedical studies have shown that genomic variations, measured with SNPs (single nucleotide polymorphisms) in genes, may have independent predictive power for disease-free survival in NHL patients beyond clinical measurements.
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