Comparative analysis and unification of domain–domain interaction networks | Zendy

Patrik Björkholm | Zendy; Erik L. L. Sonnhammer | Zendy

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Comparative analysis and unification of domain–domain interaction networks

Author(s) -

Patrik Björkholm,

Erik L. L. Sonnhammer

Publication year - 2009

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btp522

Subject(s) - computer science , merge (version control) , domain (mathematical analysis) , unification , interaction network , data mining , domain model , construct (python library) , domain analysis , artificial intelligence , theoretical computer science , domain knowledge , information retrieval , software , mathematics , mathematical analysis , biochemistry , gene , programming language , software construction , software system , chemistry

Certain protein domains are known to preferentially interact with other domains. Several approaches have been proposed to predict domain-domain interactions, and over nine datasets are available. Our aim is to analyse the coverage and quality of the existing resources, as well as the extent of their overlap. With this knowledge, we have the opportunity to merge individual domain interaction networks to construct a comprehensive and reliable database.

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