De novo transcriptome assembly with ABySS | Zendy

İnanç Birol | Zendy; Shaun D. Jackman | Zendy; Cydney Nielsen | Zendy; Jenny Q. Qian | Zendy; Richard Varhol | Zendy; Greg Stazyk | Zendy; Ryan D. Morin | Zendy; Yongjun Zhao | Zendy; Martin Hirst | Zendy; Jacqueline E. Schein | Zendy; Doug Horsman | Zendy; Joseph M. Connors | Zendy; Randy D. Gascoyne | Zendy; Marco A. Marra | Zendy; Steven J.M. Jones | Zendy

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De novo transcriptome assembly with ABySS

Author(s) -

İnanç Birol,

Shaun D. Jackman,

Cydney Nielsen,

Jenny Q. Qian,

Richard Varhol,

Greg Stazyk,

Ryan D. Morin,

Yongjun Zhao,

Martin Hirst,

Jacqueline E. Schein,

Doug Horsman,

Joseph M. Connors,

Randy D. Gascoyne,

Marco A. Marra,

Steven J.M. Jones

Publication year - 2009

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btp367

Subject(s) - contig , sequence assembly , transcriptome , genome , computational biology , java , biology , de novo transcriptome assembly , software , computer science , hybrid genome assembly , source code , shotgun sequencing , reference genome , perl , genetics , gene , programming language , gene expression

Whole transcriptome shotgun sequencing data from non-normalized samples offer unique opportunities to study the metabolic states of organisms. One can deduce gene expression levels using sequence coverage as a surrogate, identify coding changes or discover novel isoforms or transcripts. Especially for discovery of novel events, de novo assembly of transcriptomes is desirable.

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