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apLCMS—adaptive processing of high-resolution LC/MS data
Author(s) -
Tianwei Yu,
Youngja Park,
Jennifer M. Johnson,
Dean P. Jones
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp291
Subject(s) - computer science , computation , data set , filter (signal processing) , data processing , data mining , parametric statistics , pattern recognition (psychology) , algorithm , artificial intelligence , mathematics , computer vision , statistics , operating system
Liquid chromatography-mass spectrometry (LC/MS) profiling is a promising approach for the quantification of metabolites from complex biological samples. Significant challenges exist in the analysis of LC/MS data, including noise reduction, feature identification/ quantification, feature alignment and computation efficiency.

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