Open AccessA method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation
Author(s) -
Alun Thomas
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp146
Subject(s) - linkage disequilibrium , computer science , disequilibrium , linkage (software) , java , source code , computational biology , data mining , biology , single nucleotide polymorphism , genetics , gene , programming language , medicine , genotype , ophthalmology
Efficient models for genetic linkage disequilibrium (LD) are needed to enable appropriate statistical analysis of the dense, genome-wide single nucleotide polymorphism assays currently available.
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