SimMLST: simulation of multi-locus sequence typing data under a neutral model | Zendy

Xavier Didelot | Zendy; Daniel J. Lawson | Zendy; Daniel Falush | Zendy

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SimMLST: simulation of multi-locus sequence typing data under a neutral model

Author(s) -

Xavier Didelot,

Daniel J. Lawson,

Daniel Falush

Publication year - 2009

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btp145

Subject(s) - coalescent theory , multilocus sequence typing , computer science , source code , typing , license , locus (genetics) , plug in , sequence (biology) , sample (material) , graphical user interface , biology , programming language , operating system , genetics , gene , phylogenetics , physics , thermodynamics , genotype , speech recognition

Multi-locus sequence typing (MLST) is a widely used method of characterization of bacterial isolates. It has been applied to over 50,000 isolates in over 50 different species. Here, we present a coalescent method to jointly simulate MLST data and the clonal genealogy that gave rise to the sample.

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