CodonExplorer: an online tool for analyzing codon usage and sequence composition, scaling from genes to genomes
Author(s) -
Micah Hamady,
Stephanie A. Wilson,
Jesse Zaneveld,
Noboru Sueoka,
Rob Knight
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp141
Subject(s) - codon usage bias , genome , gene , gc content , function (biology) , computational biology , composition (language) , biology , genetics , linguistics , philosophy
DNA composition in general, and codon usage in particular, is crucial for understanding gene function and evolution. CodonExplorer, available online at http://bmf.colorado.edu/codonexplorer/, is an online tool and interactive database that contains millions of genes, allowing rapid exploration of the factors governing gene and genome compositional evolution and exploiting GC content and codon usage frequency to identify genes with composition suggesting high levels of expression or horizontal transfer.
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