Open AccessDetermination of sample size in genome-scale RNAi screens
Author(s) -
Xiaohua Douglas Zhang,
Joseph F. Heyse
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp082
Subject(s) - sample size determination , sample (material) , biology , rna interference , genome size , statistics , genome , scale (ratio) , genetics , computational biology , selection (genetic algorithm) , computer science , mathematics , gene , artificial intelligence , rna , physics , chromatography , chemistry , quantum mechanics
For genome-scale RNAi research, it is critical to investigate sample size required for the achievement of reasonably low false negative rate (FNR) and false positive rate.
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