Open AccessMeta-analysis of age-related gene expression profiles identifies common signatures of aging
Author(s) -
João Pedro de Magalhães,
João Curado,
George M. Church
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp073
Subject(s) - biology , gene , senescence , gene expression , microarray analysis techniques , microarray , gene expression profiling , genetics , ageing , transcriptome , computational biology , microrna , dna microarray , regulation of gene expression
Numerous microarray studies of aging have been conducted, yet given the noisy nature of gene expression changes with age, elucidating the transcriptional features of aging and how these relate to physiological, biochemical and pathological changes remains a critical problem.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom