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A novel comprehensive wave-form MS data processing method
Author(s) -
Shawn Chen,
Ming Li,
Don Hong,
Dean Billheimer,
LI Hui-ming,
Baogang Xu,
Yu Shyr
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp060
Subject(s) - computer science , preprocessor , scripting language , data mining , matlab , data pre processing , spec# , data processing , software , artificial intelligence , database , programming language
Mass spectrometry (MS) can generate high-throughput protein profiles for biomedical research to discover biologically related protein patterns/biomarkers. The noisy functional MS data collected by current technologies, however, require consistent, sensitive and robust data-processing techniques for successful biomedical application. Therefore, it is important to detect features precisely for each spectrum, quantify them well and assign a unique label to features from the same protein/peptide across spectra.

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