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A new cis-acting regulatory element driving gene expression in the zebrafish pineal gland
Author(s) -
Shahar Alon,
Eli Eisenberg,
Jasmine JacobHirsch,
Gideon Rechavi,
Gad D. Vatine,
Reiko Toyama,
Steven L. Coon,
David C. Klein,
Yoav Gothilf
Publication year - 2009
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btp031
Subject(s) - zebrafish , pineal gland , gene , element (criminal law) , gene expression , biology , regulation of gene expression , expression (computer science) , computational biology , microbiology and biotechnology , genetics , computer science , neuroscience , circadian rhythm , political science , law , programming language
The identification of functional cis-acting DNA regulatory elements is a crucial step towards understanding gene regulation. Ab initio motif detection algorithms have been extensively used in search of regulatory elements. Yet, their success in providing experimentally validated regulatory elements in vertebrates has been limited.

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