Genetic association analysis with FAMHAP: a major program update | Zendy

Christine Herold | Zendy; Tim Becker | Zendy

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Genetic association analysis with FAMHAP: a major program update

Author(s) -

Christine Herold,

Tim Becker

Publication year - 2008

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btn581

Subject(s) - international hapmap project , computer science , software , haplotype , graphical user interface , genome wide association study , genetic association , data mining , computational biology , biology , genetics , programming language , allele , single nucleotide polymorphism , genotype , gene

FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data. Furthermore, weprovide an additional program runFamhap that allows users to start the same method repeatedly for varying sets of genetic markers. In addition, a platform-independent graphical user interface (GUI) was developed to simplify the usage of both FAMHAP and runFamhap. The runFamhap program greatly facilitates the application of FAMHAP to genome-wide association studies (GWAS) and supports flexible genome-wide haplotype analysis. As an example, we describe application to HapMap data.

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