Genome annotation in the presence of insertional RNA editing | Zendy

Christina Beargie | Zendy; Tsunglin Liu | Zendy; Mark Corriveau | Zendy; Ha Youn Lee | Zendy; Jonatha M. Gott | Zendy; Ralf Bundschuh | Zendy

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Genome annotation in the presence of insertional RNA editing

Author(s) -

Christina Beargie,

Tsunglin Liu,

Mark Corriveau,

Ha Youn Lee,

Jonatha M. Gott,

Ralf Bundschuh

Publication year - 2008

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btn487

Subject(s) - physarum polycephalum , genome , gene annotation , gene , annotation , rna editing , biology , computational biology , genetics , genome project , gene prediction , rna , microbiology and biotechnology

Insertional RNA editing renders gene prediction very difficult compared to organisms without such RNA editing. A case in point is the mitochondrial genome of Physarum polycephalum in which only about one-third of the number of genes that are to be expected given its length are annotated. Thus, gene prediction methods that explicitly take into account insertional editing are needed for successful annotation of such genomes.

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