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Model-based prediction of sequence alignment quality
Author(s) -
Virpi Ahola,
Tero Aittokallio,
Mauno Vihinen,
Esa Uusipaikka
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn414
Subject(s) - multiple sequence alignment , quality score , computer science , reliability (semiconductor) , sequence (biology) , sequence alignment , set (abstract data type) , quality (philosophy) , data mining , measure (data warehouse) , score , statistics , mathematics , machine learning , biology , genetics , peptide sequence , metric (unit) , power (physics) , operations management , physics , philosophy , epistemology , quantum mechanics , gene , economics , programming language
Multiple sequence alignment (MSA) is an essential prerequisite for many sequence analysis methods and valuable tool itself for describing relationships between protein sequences. Since the success of the sequence analysis is highly dependent on the reliability of alignments, measures for assessing the quality of alignments are highly requisite.

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