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Cancer outlier detection based on likelihood ratio test
Author(s) -
Jianhua Hu
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn372
Subject(s) - outlier , r package , computer science , relevance (law) , statistical power , statistical hypothesis testing , data mining , cancer , microarray analysis techniques , likelihood ratio test , false discovery rate , artificial intelligence , pattern recognition (psychology) , statistics , mathematics , biology , gene , gene expression , computational science , political science , law , genetics , biochemistry
Microarray experiments can be used to help study the role of chromosomal translocation in cancer development through cancer outlier detection. The aim is to identify genes that are up- or down-regulated in a subset of cancer samples in comparison to normal samples.

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