Analysis of segmental duplications via duplication distance
Author(s) -
Crystal L. Kahn,
Benjamin J. Raphael
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn292
Subject(s) - gene duplication , segmental duplication , genome , computer science , biology , computational biology , genetics , gene , gene family
Segmental duplications are common in mammalian genomes, but their evolutionary origins remain mysterious. A major difficulty in analyzing segmental duplications is that many duplications are complex mosaics of fragments of numerous other segmental duplications.
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