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Clinically driven semi-supervised class discovery in gene expression data
Author(s) -
Israel Steinfeld,
Roy Navon,
Diego Ardigò,
Ivana Zavaroni,
Zohar Yakhini
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn279
Subject(s) - class (philosophy) , computational biology , computer science , gene expression , artificial intelligence , expression (computer science) , gene , data mining , biology , genetics , programming language
Unsupervised class discovery in gene expression data relies on the statistical signals in the data to exclusively drive the results. It is often the case, however, that one is interested in constraining the search space to respect certain biological prior knowledge while still allowing a flexible search within these boundaries.

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