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Improved network-based identification of protein orthologs
Author(s) -
Nir Yosef,
Roded Sharan,
William Stafford Noble
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn277
Subject(s) - identification (biology) , computer science , task (project management) , proteome , variety (cybernetics) , computational biology , code (set theory) , source code , machine learning , biology , artificial intelligence , bioinformatics , set (abstract data type) , economics , programming language , operating system , botany , management
Identifying protein orthologs is an important task that is receiving growing attention in the bioinformatics literature. Orthology detection provides a fundamental tool towards understanding protein evolution, predicting protein functions and interactions, aligning protein-protein interaction (PPI) networks of different species and detecting conserved modules within these networks.

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