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A global pathway crosstalk network
Author(s) -
Yong Li,
Pankaj Agarwal,
Dilip Rajagopalan
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn200
Subject(s) - crosstalk , computational biology , systems biology , interaction network , biological network , biology , pathway analysis , computer science , signal transduction , biological pathway , bioinformatics , gene , microbiology and biotechnology , physics , genetics , gene expression , optics
Given the complex nature of biological systems, pathways often need to function in a coordinated fashion in order to produce appropriate physiological responses to both internal and external stimuli. Therefore, understanding the interaction and crosstalk between pathways is important for understanding the function of both cells and more complex systems.

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