Peak bagging for peptide mass fingerprinting | Zendy

Zengyou He | Zendy; Can Yang | Zendy; Weichuan Yu | Zendy

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Peak bagging for peptide mass fingerprinting

Author(s) -

Zengyou He,

Can Yang,

Weichuan Yu

Publication year - 2008

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btn123

Subject(s) - peptide mass fingerprinting , identification (biology) , computer science , tandem mass spectrometry , proteome , mass spectrometry , tandem , tandem mass tag , chemistry , proteomics , chromatography , quantitative proteomics , biology , materials science , composite material , gene , biochemistry , botany

Mass Spectrometry (MS)-based protein identification via peptide mass fingerprinting (PMF) is a key component in high-throughput proteome research. While PMF was the first commonly used protein identification method, provided higher throughput than the tandem MS-based method, its accuracy is lower than that of the tandem MS method. Thus, it is desirable to develop PMF-based algorithm with higher protein identification accuracy to facilitate proteome research.

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