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Biological sequence classification utilizing positive and unlabeled data
Author(s) -
Yuanyuan Xiao,
Mark R. Segal
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btn089
Subject(s) - computer science , context (archaeology) , class (philosophy) , cluster analysis , set (abstract data type) , data mining , artificial intelligence , data set , sequence (biology) , identification (biology) , property (philosophy) , pattern recognition (psychology) , machine learning , paleontology , philosophy , genetics , botany , epistemology , biology , programming language
In the genomics setting, an increasingly common data configuration consists of a small set of sequences possessing a targeted property (positive instances) amongst a large set of sequences for which class membership is unknown (unlabeled instances). Traditional two-class classification methods do not effectively handle such data.

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