A note on difficult structure alignment problems | Zendy

Manfred J. Sippl | Zendy; Markus Wiederstein | Zendy

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A note on difficult structure alignment problems

Author(s) -

Manfred J. Sippl,

Markus Wiederstein

Publication year - 2008

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm622

Subject(s) - computer science , visualization , key (lock) , web service , superposition principle , service (business) , protein structure , structural biology , data science , world wide web , artificial intelligence , biology , mathematics , genetics , biochemistry , computer security , economy , economics , mathematical analysis

Progress in structural biology depends on several key technologies. In particular tools for alignment and superposition of protein structures are indispensable. Here we describe the use of the TopMatch web service, an effective computational tool for protein structure alignment, for the visualization of structural similarities, and for highlighting relationships found in protein classifications. We provide several instructive examples.

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