Prediction of both conserved and nonconserved microRNA targets in animals
Author(s) -
Xiaowei Wang,
Issam El Naqa
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm595
Subject(s) - microrna , computational biology , computer science , biology , genetics , gene
MicroRNAs (miRNAs) are involved in many diverse biological processes and they may potentially regulate the functions of thousands of genes. However, one major issue in miRNA studies is the lack of bioinformatics programs to accurately predict miRNA targets. Animal miRNAs have limited sequence complementarity to their gene targets, which makes it challenging to build target prediction models with high specificity.
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