Probabilistic path ranking based on adjacent pairwise coexpression for metabolic transcripts analysis
Author(s) -
Ichigaku Takigawa,
Hiroshi Mamitsuka
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm575
Subject(s) - pairwise comparison , ranking (information retrieval) , probabilistic logic , path (computing) , path analysis (statistics) , computer science , computational biology , data mining , statistics , biology , mathematics , artificial intelligence , machine learning , programming language
Pathway knowledge in public databases enables us to examine how individual metabolites are connected via chemical reactions and what genes are implicated in those processes. For two given (sets of) compounds, the number of possible paths between them in a metabolic network can be intractably large. It would be informative to rank these paths in order to differentiate between them.
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